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Toll-like Receptor 9–Dependent and –Independent Dendritic Cell Activation by Chromatin–Immunoglobulin G Complexes

Dendritic cell (DC) activation by nucleic acid–containing immunoglobulin (Ig)G complexes has been implicated in systemic lupus erythematosus (SLE) pathogenesis. However, the mechanisms responsible for activation and subsequent disease induction are not completely understood. Here we show that murine...

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Detalhes bibliográficos
Main Authors: Boulé, Melissa W., Broughton, Courtney, Mackay, Fabienne, Akira, Shizuo, Marshak-Rothstein, Ann, Rifkin, Ian R.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212813/
https://ncbi.nlm.nih.gov/pubmed/15197227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031942
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