Role of β2-integrins for homing and neovascularization capacity of endothelial progenitor cells

The mechanisms of homing of endothelial progenitor cells (EPCs) to sites of ischemia are unclear. Here, we demonstrate that ex vivo–expanded EPCs as well as murine hematopoietic Sca-1(+)/Lin(−) progenitor cells express β2-integrins, which mediate the adhesion of EPCs to endothelial cell monolayers a...

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Detalhes bibliográficos
Main Authors: Chavakis, Emmanouil, Aicher, Alexandra, Heeschen, Christopher, Sasaki, Ken-ichiro, Kaiser, Ralf, El Makhfi, Naual, Urbich, Carmen, Peters, Thorsten, Scharffetter-Kochanek, Karin, Zeiher, Andreas M., Chavakis, Triantafyllos, Dimmeler, Stefanie
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2005
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212777/
https://ncbi.nlm.nih.gov/pubmed/15623573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041402
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