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Stability and Kinetic Properties of C5-Domain from Myosin Binding Protein C and its Mutants
The impact of three mutations of domain C5 from myosin binding protein C, correlated to Familial Hypertrophic Cardiomyopathy, has been assessed through molecular dynamics simulations based on a native centric protein modeling. The severity of the phenotype correlates with the shift in unfolding temp...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Biophysical Society
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2212681/ https://ncbi.nlm.nih.gov/pubmed/17965135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.106625 |
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