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Detection of short repeated genomic sequences on metaphase chromosomes using padlock probes and target primed rolling circle DNA synthesis

BACKGROUND: In situ detection of short sequence elements in genomic DNA requires short probes with high molecular resolution and powerful specific signal amplification. Padlock probes can differentiate single base variations. Ligated padlock probes can be amplified in situ by rolling circle DNA synt...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lohmann, Jakob S, Stougaard, Magnus, Koch, Jørn
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2007
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212658/
https://ncbi.nlm.nih.gov/pubmed/17997865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-8-103
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