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Repeated BCG treatment of mouse bladder selectively stimulates small GTPases and HLA antigens and inhibits single-spanning uroplakins

BACKGROUND: Despite being a mainstay for treating superficial bladder carcinoma and a promising agent for interstitial cystitis, the precise mechanism of Bacillus Calmette-Guerin (BCG) remains poorly understood. It is particularly unclear whether BCG is capable of altering gene expression beyond its...

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Detalhes bibliográficos
Main Authors: Saban, Marcia R, Hellmich, Helen L, Simpson, Cindy, Davis, Carole A, Lang, Mark L, Ihnat, Michael A, O'Donnell, Michael A, Wu, Xue-Ru, Saban, Ricardo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212656/
https://ncbi.nlm.nih.gov/pubmed/17980030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-7-204
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