Insights into spatial configuration of a galactosylated epitope required to trigger arthritogenic T-cell receptors specific for the sugar moiety

The immunodominant epitope of bovine type II collagen (CII256–270) in A(q )mice carries a hydroxylysine-264 linked galactose (Gal-Hyl(264)), the recognition of which is central to the development of collagen-induced arthritis. This study explores the molecular interactions involved in the engagement...

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Autori principali: Glatigny, Simon, Blaton, Marie-Agnès, Marin, Julien, Mistou, Sylvie, Briand, Jean-Paul, Guichard, Gilles, Fournier, Catherine, Chiocchia, Gilles
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2007
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212564/
https://ncbi.nlm.nih.gov/pubmed/17848196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2291
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