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Translation of a Retained Intron in Tyrosinase-related Protein (TRP) 2 mRNA Generates a New Cytotoxic T Lymphocyte (CTL)-defined and Shared Human Melanoma Antigen Not Expressed in Normal Cells of the Melanocytic Lineage

We report here the identification of a new shared human melanoma antigen recognized by a human leukocyte antigen (HLA)-A*68011–restricted cytotoxic T lymphocyte clone (CTL 128). The cDNA encoding this antigen is composed of a partially spliced form of the melanocyte differentiation antigen tyrosinas...

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Detalhes bibliográficos
Main Authors: Lupetti, Raffaella, Pisarra, Patrizia, Verrecchia, Alessandro, Farina, Cinthia, Nicolini, Gabriella, Anichini, Andrea, Bordignon, Claudio, Sensi, Marialuisa, Parmiani, Giorgio, Traversari, Catia
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212536/
https://ncbi.nlm.nih.gov/pubmed/9743519
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