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Transendothelial Migration of Megakaryocytes in Response to Stromal Cell-derived Factor 1 (SDF-1) Enhances Platelet Formation

Although thrombopoietin has been shown to promote megakaryocyte (MK) proliferation and maturation, the exact mechanism and site of platelet formation are not well defined. Studies have shown that MKs may transmigrate through bone marrow endothelial cells (BMEC), and release platelets within the sinu...

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Bibliografiske detaljer
Main Authors: Hamada, Tsuneyoshi, Möhle, Robert, Hesselgesser, Joseph, Hoxie, James, Nachman, Ralph L., Moore, Malcolm A.S., Rafii, Shahin
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212480/
https://ncbi.nlm.nih.gov/pubmed/9687531
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