HIV-1 Antigen–specific and –nonspecific B Cell Responses Are Sensitive to Combination Antiretroviral Therapy

We studied how combination antiviral therapy affects B cell abnormalities associated with HIV-1 infection, namely elevated circulating immunoglobulin (Ig)G antibody-secreting cell (ASC) frequencies and hypergammaglobulinemia. Within a few weeks of starting antiviral therapy, there is a marked declin...

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Main Authors: Morris, Lynn, Binley, James M., Clas, Brian A., Bonhoeffer, Sebastian, Astill, Thomas P., Kost, Rhonda, Hurley, Arlene, Cao, Yunzhen, Markowitz, Martin, Ho, David D., Moore, John P.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 1998
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212446/
https://ncbi.nlm.nih.gov/pubmed/9670036
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