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Interleukin 7 Receptor Control of  T Cell Receptor γ Gene Rearrangement: Role of Receptor-associated Chains and Locus Accessibility

VDJ recombination of T cell receptor and immunoglobulin loci occurs in immature lymphoid cells. Although the molecular mechanisms of DNA cleavage and ligation have become more clear, it is not understood what controls which target loci undergo rearrangement. In interleukin 7 receptor (IL-7R)α(−/−) m...

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Dettagli Bibliografici
Autori principali: Durum, Scott K., Candèias, Serge, Nakajima, Hiroshi, Leonard, Warren J., Baird, Allison M., Berg, Leslie J., Muegge, Kathrin
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212428/
https://ncbi.nlm.nih.gov/pubmed/9858510
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