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Visualization of CD4/CD8 T Cell Commitment

A system to innocuously visualize T cell lineage commitment is described. Using a “knock-in” approach, we have generated mice expressing a β-galactosidase reporter in place of CD4; expression of β-galactosidase in these animals appears to be an accurate and early indicator of CD4 gene transcription....

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Bibliografische gegevens
Hoofdauteurs: Chan, Susan, Correia-Neves, Margarida, Dierich, Andrée, Benoist, Christophe, Mathis, Diane
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 1998
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212422/
https://ncbi.nlm.nih.gov/pubmed/9858518
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