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CD4(+) T Cells Prevent Spontaneous Experimental Autoimmune Encephalomyelitis in Anti–Myelin Basic Protein T Cell Receptor Transgenic Mice

Autoimmune diseases result from a failure of tolerance. Although many self-reactive T cells are present in animals and humans, their activation appears to be prevented normally by regulatory T cells. In this study, we show that regulatory CD4(+) T cells do protect mice against the spontaneous occurr...

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Détails bibliographiques
Auteurs principaux: Van de Keere, Fabienne, Tonegawa, Susumu
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212404/
https://ncbi.nlm.nih.gov/pubmed/9815265
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