Llwytho...

Expression of Constitutively Active Raf-1 in the Mitochondria Restores Antiapoptotic and Leukemogenic Potential of a Transformation-deficient BCR/ABL Mutant

The oncogenic BCR/ABL protein protects hematopoietic cells from apoptosis induced by growth factor deprivation, but the mechanisms are only partially understood. A BCR/ABL mutant lacking amino acids 176–426 in the BCR domain (p185ΔBCR) failed to protect interleukin 3–deprived 32Dcl3 myeloid precurso...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Salomoni, Paolo, Wasik, Mariusz A., Riedel, Richard F., Reiss, Krzysztof, Choi, John K., Skorski, Tomasz, Calabretta, Bruno
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 1998
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212373/
https://ncbi.nlm.nih.gov/pubmed/9625759
Tagiau: Ychwanegu Tag
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