Evidence That the Autoimmune Antigen Myelin Basic Protein (MBP) Ac1-9 Binds Towards One End of the Major Histocompatibility Complex (MHC) Cleft

The NH(2)-terminal peptide of myelin basic protein (MBP) bound to the class II major histocompatibility complex (MHC) protein I-A(u) is an immunodominant epitope in experimental autoimmune encephalomyelitis, a murine model of multiple sclerosis. However, the MBP–I-A(u) complex is very unstable. To i...

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Hlavní autoři: Lee, Christopher, Liang, Michael N., Tate, Keri M., Rabinowitz, Joshua D., Beeson, Craig, Jones, Patricia P., McConnell, Harden M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 1998
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212267/
https://ncbi.nlm.nih.gov/pubmed/9565642
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