Abrogation of Bronchial Eosinophilic Inflammation and Airway Hyperreactivity in Signal Transducers and Activators of Transcription (STAT)6-deficient Mice

Signal transducers and activators of transcription 6 (STAT6) is essential for interleukin 4–mediated responses, including class switching to IgE and induction of type 2 T helper cells. To investigate the role of STAT6 in allergic asthma in vivo, we developed a murine model of allergen-induced airway...

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Main Authors: Akimoto, Toshihiko, Numata, Fumio, Tamura, Misato, Takata, Yoshimi, Higashida, Noriko, Takashi, Tohru, Takeda, Kiyoshi, Akira, Shizuo
格式: Artigo
語言:Inglês
出版: The Rockefeller University Press 1998
主題:
Brief Definitive Report
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212260/
https://ncbi.nlm.nih.gov/pubmed/9565645
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