Nucleoside Analogue Reverse Transcriptase Inhibitors Differentially Inhibit Human LINE-1 Retrotransposition

BACKGROUND: Intact LINE-1 elements are the only retrotransposons encoded by the human genome known to be capable of autonomous replication. Numerous cases of genetic disease have been traced to gene disruptions caused by LINE-1 retrotransposition events in germ-line cells. In addition, genomic insta...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Jones, R. Brad, Garrison, Keith E., Wong, Jessica C., Duan, Erick H., Nixon, Douglas F., Ostrowski, Mario A.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2008
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212136/
https://ncbi.nlm.nih.gov/pubmed/18253495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0001547
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki