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Endogenous Interleukin 4 Is Required for Development of Protective CD4(+) T Helper Type 1 Cell Responses to Candida albicans

Interleukin (IL)-4–deficient mice were used to assess susceptibility to systemic or gastrointestinal Candida albicans infections, as well as parameters of innate and elicited T helper immunity. In the early stage of systemic infection with virulent C. albicans, an unopposed interferon (IFN)-γ respon...

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Detalhes bibliográficos
Main Authors: Mencacci, Antonella, Del Sero, Giuseppe, Cenci, Elio, d'Ostiani, Cristiana Fè, Bacci, Angela, Montagnoli, Claudia, Kopf, Manfred, Romani, Luigina
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2212115/
https://ncbi.nlm.nih.gov/pubmed/9449711
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