Mycobacterium tuberculosis pks12 Produces a Novel Polyketide Presented by CD1c to T Cells

CD1c-mediated T cells are activated by a mycobacterial phospholipid antigen whose carbohydrate structure precisely corresponds to mammalian mannosyl β-1-phosphodolichol (MPD), but contains an unusual lipid moiety. Here, we show that this T cell antigen is a member of a family of branched, alkane lip...

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Bibliografiske detaljer
Main Authors: Matsunaga, Isamu, Bhatt, Apoorva, Young, David C., Cheng, Tan-Yun, Eyles, Stephen J., Besra, Gurdyal S., Briken, Volker, Porcelli, Steven A., Costello, Catherine E., Jacobs, William R., Moody, D. Branch
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2004
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211992/
https://ncbi.nlm.nih.gov/pubmed/15611286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041429
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