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CD4(+) T Cell Depletion during all Stages of HIV Disease Occurs Predominantly in the Gastrointestinal Tract

The mechanisms underlying CD4(+) T cell depletion in human immunodeficiency virus (HIV) infection are not well understood. Comparative studies of lymphoid tissues, where the vast majority of T cells reside, and peripheral blood can potentially illuminate the pathogenesis of HIV-associated disease. H...

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Detalhes bibliográficos
Main Authors: Brenchley, Jason M., Schacker, Timothy W., Ruff, Laura E., Price, David A., Taylor, Jodie H., Beilman, Gregory J., Nguyen, Phuong L., Khoruts, Alexander, Larson, Matthew, Haase, Ashley T., Douek, Daniel C.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211962/
https://ncbi.nlm.nih.gov/pubmed/15365096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20040874
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