DC-SIGN–mediated Infectious Synapse Formation Enhances X4 HIV-1 Transmission from Dendritic Cells to T Cells

Dendritic cells (DCs) are essential for the early events of human immunodeficiency virus (HIV) infection. Model systems of HIV sexual transmission have shown that DCs expressing the DC-specific C-type lectin DC-SIGN capture and internalize HIV at mucosal surfaces and efficiently transfer HIV to CD4(...

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Главные авторы: Arrighi, Jean-François, Pion, Marjorie, Garcia, Eduardo, Escola, Jean-Michel, van Kooyk, Yvette, Geijtenbeek, Teunis B., Piguet, Vincent
Формат: Artigo
Язык:Inglês
Опубликовано: The Rockefeller University Press 2004
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211914/
https://ncbi.nlm.nih.gov/pubmed/15545354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041356
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