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T Cell–specific Inactivation of the Interleukin 10 Gene in Mice Results in Enhanced T Cell Responses but Normal Innate Responses to Lipopolysaccharide or Skin Irritation

Interleukin (IL)-10 is a regulator of inflammatory responses and is secreted by a variety of different cell types including T cells. T regulatory cells have been shown to suppress immune responses by IL-10–dependent, but also IL-10–independent, mechanisms. Herein, we address the role of T cell–deriv...

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Hlavní autoři: Roers, Axel, Siewe, Lisa, Strittmatter, Elke, Deckert, Martina, Schlüter, Dirk, Stenzel, Werner, Gruber, Achim D., Krieg, Thomas, Rajewsky, Klaus, Müller, Werner
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2004
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211912/
https://ncbi.nlm.nih.gov/pubmed/15534372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20041789
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