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Potentiation of C1 Esterase Inhibitor by StcE, a Metalloprotease Secreted by Escherichia coli O157:H7

The complement system is an essential component of host defense against pathogens. Previous research in our laboratory identified StcE, a metalloprotease secreted by Escherichia coli O157:H7 that cleaves the serpin C1 esterase inhibitor (C1-INH), a major regulator of the classical complement cascade...

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Autors principals: Lathem, Wyndham W., Bergsbaken, Tessa, Welch, Rodney A.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211892/
https://ncbi.nlm.nih.gov/pubmed/15096536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20030255
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