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Editing Anti-DNA B Cells by Vλx
Receptor editing is performed by replacement of Vκ genes that contribute to autoreactivity. In addition, the Cκ locus can be deleted by Vκ rearrangement to intronic or 3′ of Cκ RS sequences (also referred to as κ deletion elements). B cells that delete the Cκ can then express λ light chains. However...
Wedi'i Gadw mewn:
| Prif Awduron: | , , |
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| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
The Rockefeller University Press
2004
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2211795/ https://ncbi.nlm.nih.gov/pubmed/14757741 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20031712 |
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