Distinct Time Effects of Vaccination on Long-Term Proliferative and IFN-γ–producing T Cell Memory to Smallpox in Humans

Residual immunity to the smallpox virus raises key questions about the persistence of long-term immune memory in the absence of antigen, since vaccination ended in 1980. IFN-γ–producing effector–memory and proliferative memory T cells were compared in 79 vaccinees 13–25 yr after their last immunizat...

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Bibliographic Details
Main Authors: Combadiere, Behazine, Boissonnas, Alexandre, Carcelain, Guislaine, Lefranc, Evelyne, Samri, Assia, Bricaire, François, Debre, Patrice, Autran, Brigitte
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2004
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211784/
https://ncbi.nlm.nih.gov/pubmed/15184506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20032083
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