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Rapid cognitive improvement in Alzheimer's disease following perispinal etanercept administration

Substantial basic science and clinical evidence suggests that excess tumor necrosis factor-alpha (TNF-alpha) is centrally involved in the pathogenesis of Alzheimer's disease. In addition to its pro-inflammatory functions, TNF-alpha has recently been recognized to be a gliotransmitter that regul...

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Bibliographic Details
Main Authors: Tobinick, Edward L, Gross, Hyman
Format: Artigo
Language:Inglês
Published: BioMed Central 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211476/
https://ncbi.nlm.nih.gov/pubmed/18184433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-5-2
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