Five distinct biological processes and 14 differentially expressed genes characterize TEL/AML1-positive leukemia

BACKGROUND: The t(12;21)(p13;q22) translocation is found in 20 to 25% of cases of childhood B-lineage acute lymphoblastic leukemia (B-ALL). This rearrangement results in the fusion of ETV6 (TEL) and RUNX1 (AML1) genes and defines a relatively uniform category, although only some patients suffer very...

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Huvudupphovsmän: Gandemer, Virginie, Rio, Anne-Gaëlle, de Tayrac, Marie, Sibut, Vonnick, Mottier, Stéphanie, Ly Sunnaram, Béatrice, Henry, Catherine, Monnier, Annabelle, Berthou, Christian, Le Gall, Edouard, Le Treut, André, Schmitt, Claudine, Le Gall, Jean-Yves, Mosser, Jean, Galibert, Marie-Dominique
Materialtyp: Artigo
Språk:Inglês
Publicerad: BioMed Central 2007
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211320/
https://ncbi.nlm.nih.gov/pubmed/17956600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-8-385
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