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Dermal fibroblasts derived from fetal and postnatal humans exhibit distinct responses to insulin like growth factors

BACKGROUND: It has been well established that human fetuses will heal cutaneous wounds with perfect regeneration. Insulin-like growth factors are pro-fibrotic fibroblast mitogens that have important roles in both adult wound healing and during development, although their relative contribution toward...

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Bibliografiske detaljer
Main Authors: Rolfe, Kerstin J, Cambrey, Alison D, Richardson, Janette, Irvine, Laurie M, Grobbelaar, Adriaan O, Linge, Claire
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2211318/
https://ncbi.nlm.nih.gov/pubmed/17988375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-7-124
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