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Cytolytic and IFN-γ-producing activities of γδ T cells in the mouse intestinal epithelium are T cell receptor-β-chain dependent

We analyzed the cytolytic activity of intraepithelial T cells (IEL) isolated from the small intestines of 2- to 3-month-old mutant mice rendered deficient in different gene(s) in which the number of IEL expressing either T cell receptor (TCR)-αβ (αβ-IEL) or TCR-γδ (γδ-IEL) were absent or markedly di...

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Detalhes bibliográficos
Main Authors: Kohyama, Masako, Nanno, Masanobu, Kawaguchi-Miyashita, Mariko, Shimada, Shinichiro, Watanabe, Mamoru, Hibi, Toshifumi, Kaminogawa, Schuichi, Ishikawa, Hiromichi
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC22106/
https://ncbi.nlm.nih.gov/pubmed/10377435
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