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Separation of C/EBPα-mediated proliferation arrest and differentiation pathways

Cell proliferation and terminal differentiation are mutually exclusive in most cell lineages. The b-zip transcription factor CCAAT/enhancer-binding protein α (C/EBPα) induces proliferation arrest and differentiation in many cell types, suggesting that both activities are linked. Here we show that C/...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Müller, Christine, Alunni-Fabbroni, Marianna, Kowenz-Leutz, Elisabeth, Mo, Xianming, Tommasino, Massimo, Leutz, Achim
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1999
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22076/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10377405/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.13.7276
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