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Modeling mutations in protein structures

We describe an automated method for the modeling of point mutations in protein structures. The protein is represented by all non-hydrogen atoms. The scoring function consists of several types of physical potential energy terms and homology-derived restraints. The optimization method implements a com...

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Detalhes bibliográficos
Main Authors: Feyfant, Eric, Sali, Andrej, Fiser, András
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley-Blackwell 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206969/
https://ncbi.nlm.nih.gov/pubmed/17766392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.072855507
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