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The active form of the steroidogenic acute regulatory protein, StAR, appears to be a molten globule

The steroidogenic acute regulatory protein (StAR) increases the movement of cholesterol from the outer to the inner membrane of adrenal and gonadal mitochondria, thus providing the substrate for steroid hormone biosynthesis. Deletion of 62 amino-terminal aa produces a cytoplasmic form of StAR (N-62...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Bose, Himangshu S., Whittal, Randy M., Baldwin, Michael A., Miller, Walter L.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1999
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC22068/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10377400/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.13.7250
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