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A high-throughput method for membrane protein solubility screening: The ultracentrifugation dispersity sedimentation assay
One key to successful crystallization of membrane proteins is the identification of detergents that maintain the protein in a soluble, monodispersed state. Because of their hydrophobic nature, membrane proteins are particularly prone to forming insoluble aggregates over time. This nonspecific aggreg...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2206705/ https://ncbi.nlm.nih.gov/pubmed/17567744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.072759907 |
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