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Corticotropin-releasing hormone deficiency unmasks the proinflammatory effect of epinephrine

Traditionally, the adrenal gland has been considered an important endocrine component of the pathway to inhibit acute inflammation via hypothalamic corticotropin-releasing hormone (CRH)-mediated secretion of glucocorticoid. Immunoreactive CRH found in inflamed tissues is a potent proinflammatory fac...

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Main Authors: Karalis, Katia P., Kontopoulos, Effie, Muglia, Louis J., Majzoub, Joseph A.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 1999
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC22067/
https://ncbi.nlm.nih.gov/pubmed/10359844
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