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Estrogen receptor–ligand complexes measured by chip-based nanoelectrospray mass spectrometry: An approach for the screening of endocrine disruptors

In the present report, a method based on chip-based nanoelectrospray mass spectrometry (nanoESI-MS) is described to detect noncovalent ligand binding to the human estrogen receptor α ligand-binding domain (hERα LBD). This system represents an important environmental interest, because a wide variety...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bovet, Cédric, Wortmann, Arno, Eiler, Sylvia, Granger, Florence, Ruff, Marc, Gerrits, Bertran, Moras, Dino, Zenobi, Renato
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206638/
https://ncbi.nlm.nih.gov/pubmed/17400923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062664107
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