Eoxins are proinflammatory arachidonic acid metabolites produced via the 15-lipoxygenase-1 pathway in human eosinophils and mast cells

Human eosinophils contain abundant amounts of 15-lipoxygenase (LO)-1. The biological role of 15-LO-1 in humans, however, is unclear. Incubation of eosinophils with arachidonic acid led to formation of a product with a UV absorbance maximum at 282 nm and shorter retention time than leukotriene (LT)C(...

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Autori principali: Feltenmark, Stina, Gautam, Narinder, Brunnström, Åsa, Griffiths, William, Backman, Linda, Edenius, Charlotte, Lindbom, Lennart, Björkholm, Magnus, Claesson, Hans-Erik
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206596/
https://ncbi.nlm.nih.gov/pubmed/18184802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0710127105
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