Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis

Here we report the effects of loss of the Toll-like receptor-associated signaling adaptor myeloid-differentiation factor 88 (MyD88) on tumor induction in two distinct mouse models of carcinogenesis. The 7,12-dimethylbenz[a]anthracene (DMBA)/12-O-tetradecanoylphorbol 13-acetate (TPA)-induced skin pap...

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Detalhes bibliográficos
Main Authors: Swann, Jeremy B., Vesely, Matthew D., Silva, Anabel, Sharkey, Janelle, Akira, Shizuo, Schreiber, Robert D., Smyth, Mark J.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206591/
https://ncbi.nlm.nih.gov/pubmed/18178624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0708594105
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