Germ-line mutations, DNA damage, and global hypermethylation in mice exposed to particulate air pollution in an urban/industrial location

Particulate air pollution is widespread, yet we have little understanding of the long-term health implications associated with exposure. We investigated DNA damage, mutation, and methylation in gametes of male mice exposed to particulate air pollution in an industrial/urban environment. C57BL/CBA mi...

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Bibliografiska uppgifter
Huvudupphovsmän: Yauk, Carole, Polyzos, Aris, Rowan-Carroll, Andrea, Somers, Christopher M., Godschalk, Roger W., Van Schooten, Frederik J., Berndt, M. Lynn, Pogribny, Igor P., Koturbash, Igor, Williams, Andrew, Douglas, George R., Kovalchuk, Olga
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2008
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206583/
https://ncbi.nlm.nih.gov/pubmed/18195365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705896105
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