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Effect of dsDNA binding to SmD-derived peptides on clinical accuracy in the diagnosis of systemic lupus erythematosus

Systemic lupus erythematosus is characterized by antibodies to a variety of intracellular self-antigens, such as dsDNA and Sm, and these serve as hallmarks in the diagnosis of systemic autoimmune diseases. Several studies have shown that SmD1 and SmD3 synthetic peptides represent highly functional a...

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Autori principali: Mahler, Michael, Waka, Aderajew, Hiepe, F, Fritzler, Marvin J
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206372/
https://ncbi.nlm.nih.gov/pubmed/17640359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2266
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