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Major biological obstacles for persistent cell-based regeneration of articular cartilage

Hyaline articular cartilage, the load-bearing tissue of the joint, has very limited repair and regeneration capacities. The lack of efficient treatment modalities for large chondral defects has motivated attempts to engineer cartilage constructs in vitro by combining cells, scaffold materials and en...

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Autori principali: Steinert, Andre F, Ghivizzani, Steven C, Rethwilm, Axel, Tuan, Rocky S, Evans, Christopher H, Nöth, Ulrich
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206353/
https://ncbi.nlm.nih.gov/pubmed/17561986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2195
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