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Major biological obstacles for persistent cell-based regeneration of articular cartilage

Hyaline articular cartilage, the load-bearing tissue of the joint, has very limited repair and regeneration capacities. The lack of efficient treatment modalities for large chondral defects has motivated attempts to engineer cartilage constructs in vitro by combining cells, scaffold materials and en...

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Main Authors: Steinert, Andre F, Ghivizzani, Steven C, Rethwilm, Axel, Tuan, Rocky S, Evans, Christopher H, Nöth, Ulrich
格式: Artigo
語言:Inglês
出版: BioMed Central 2007
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206353/
https://ncbi.nlm.nih.gov/pubmed/17561986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2195
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