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Characterization, developmental expression and evolutionary features of the huntingtin gene in the amphioxus Branchiostoma floridae

BACKGROUND: Huntington's disease is an inherited neurodegenerative disorder that is caused by the expansion of an N-terminal polyQ stretch in the huntingtin protein. In order to investigate the hypothesis that huntingtin was already involved in development of the nervous system in the last comm...

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Autors principals: Candiani, Simona, Pestarino, Mario, Cattaneo, Elena, Tartari, Marzia
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2206037/
https://ncbi.nlm.nih.gov/pubmed/18005438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-213X-7-127
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