Polyclonal anti-idiotypic antibodies mimicking the small cell lung carcinoma antigen cluster-5A interact with a panel of antibodies and induce specific immune response in animals.

Polyclonal anti-idiotypic antibodies (ab2) were generated by immunising goats with the murine IgG2a monoclonal antibody SWA20 which recognises the SCLC antigen cluster-5A, a tumour-associated sialoglycoprotein. Ab2 was shown to bind specifically to antibody SWA20, but not to isotype matched control...

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Autores principales: Zwicky, C., Stahel, R. A., Jaksche, H., Waibel, R., Lehmann, H. P., Loibner, H.
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 1991
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2204093/
https://ncbi.nlm.nih.gov/pubmed/1645576
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