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Post-Pubertal Disruption of Medial Prefrontal Cortical Dopamine–Glutamate Interactions in a Developmental Animal Model of Schizophrenia

BACKGROUND: A neonatal ventral hippocampal lesion (NVHL) induces behavioral and physiological anomalies mimicking pathophysiological changes of schizophrenia. Because prefrontal cortical (PFC) pyramidal neurons recorded from adult NVHL rats exhibit abnormal responses to activation of the mesocortica...

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Main Authors: Tseng, Kuei-Yuan, Lewis, Barbara L., Lipska, Barbara K., O’Donnell, Patricio
Format: Artigo
Jezik:Inglês
Izdano: 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2204086/
https://ncbi.nlm.nih.gov/pubmed/17207473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biopsych.2006.10.012
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