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Differentiated Horizontal Interneurons Clonally Expand to Form Metastatic Retinoblastoma in Mice

During neurogenesis, the progression from a progenitor cell to a differentiated neuron is believed to be unidirectional and irreversible. The Rb family of proteins (Rb, p107 and p130) regulates cell cycle exit and differentiation during retinogenesis. Rb and p130 are redundantly expressed in the neu...

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Bibliographic Details
Main Authors: Ajioka, Itsuki, Martins, Rodrigo A.P., Bayazitov, Ildar T., Donovan, Stacy, Johnson, Dianna A., Frase, Sharon, Cicero, Samantha, Boyd, Kelli, Zakharenko, Stanislav S., Dyer, Michael A.
Format: Artigo
Language:Inglês
Published: 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2203617/
https://ncbi.nlm.nih.gov/pubmed/17956737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2007.09.036
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