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Toward rational protein crystallization: A Web server for the design of crystallizable protein variants

Growing well-diffracting crystals constitutes a serious bottleneck in structural biology. A recently proposed crystallization methodology for “stubborn crystallizers” is to engineer surface sequence variants designed to form intermolecular contacts that could support a crystal lattice. This approach...

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Main Authors: Goldschmidt, Lukasz, Cooper, David R., Derewenda, Zygmunt S., Eisenberg, David
Format: Artigo
Jezik:Inglês
Izdano: Cold Spring Harbor Laboratory Press 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2203352/
https://ncbi.nlm.nih.gov/pubmed/17656576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.072914007
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