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Covalent heme attachment in Synechocystis hemoglobin is required to prevent ferrous heme dissociation

Synechocystis hemoglobin contains an unprecedented covalent bond between a nonaxial histidine side chain (H117) and the heme 2-vinyl. This bond has been previously shown to stabilize the ferric protein against denaturation, and also to affect the kinetics of cyanide association. However, it is uncle...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hoy, Julie A., Smagghe, Benoit J., Halder, Puspita, Hargrove, Mark S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2203299/
https://ncbi.nlm.nih.gov/pubmed/17242429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.062572607
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