Augmented hyperemia and reduced tissue injury in response to ischemia in subjects with the 34C > T variant of the AMPD1 gene

INTRODUCTION: In patients with cardiovascular disease the 34C > T variant of the adenosine monophosphate deaminase (AMPD1) gene is associated with improved survival. We hypothesized that this variant results in enhanced intracellular formation of adenosine during ischemia, thereby increasing hype...

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Bibliographic Details
Main Authors: Riksen, N P, Franke, B, Oyen, W J G, van den Broek, P, Boerman, O C, Smits, P, Rongen, G A
Format: Artigo
Language:Inglês
Published: Blackwell Publishing Ltd 2007
Subjects:
Proceedings of the Dutch Society of Clinical Pharmacology and Biopharmacy meeting of September 27th 2006
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2203232/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2007.02886_6.x
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