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Broad tumor-associated expression and recognition by tumor-derived γδ T cells of MICA and MICB

Human MHC class I-related molecules, MICA and MICB, are stress-induced antigens that are recognized by a subset of γδ T cells expressing the variable region V(δ)1. This functional association has been found to be limited to intestinal epithelium, where these T cells are prevalent and where MICA and,...

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Autores principales: Groh, Veronika, Rhinehart, Rebecca, Secrist, Heather, Bauer, Stefan, Grabstein, Kenneth H., Spies, Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 1999
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC22010/
https://ncbi.nlm.nih.gov/pubmed/10359807
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