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Taking ALPS down a Notch
Notch activation is an early and critical event during T-cell leukemogenesis, hence Notch signal inhibition is a desirable and feasible intervention to abrogate the process of lymphocyte accumulation and antibody production secondary to apoptosis defects as shown in 2 murine models here. However, pr...
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Hematology
2008
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| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2200844/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-10-119479 |
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