Intravenous immunoglobulins reverse acute vaso-occlusive crises in sickle cell mice through rapid inhibition of neutrophil adhesion

Previous studies using intravital microscopy in a sickle cell disease (SCD) mouse model suggest that adherent white blood cells (WBCs) play a key role in vaso-occlusion by capturing circulating red blood cells (RBCs) in venules. Commercial intravenous immunoglobulin (IVIG) given before the inflammat...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chang, Jungshan, Shi, Patricia A., Chiang, Elaine Y., Frenette, Paul S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2008
Gaiak:
Red Cells
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200843/
https://ncbi.nlm.nih.gov/pubmed/17932253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-04-084061
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