HIV-1–induced activation of CD4(+) T cells creates new targets for HIV-1 infection in human lymphoid tissue ex vivo

We demonstrate mechanisms by which HIV-1 appears to facilitate its own infection in ex vivo–infected human lymphoid tissue. In this system, HIV-1 readily infects various CD4(+) T cells, but productive viral infection was supported predominantly by activated T cells expressing either CD25 or HLA-DR o...

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Autori principali: Biancotto, Angélique, Iglehart, Sarah J., Vanpouille, Christophe, Condack, Cristian E., Lisco, Andrea, Ruecker, Elke, Hirsch, Ivan, Margolis, Leonid B., Grivel, Jean-Charles
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2008
Soggetti:
Immunobiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2200839/
https://ncbi.nlm.nih.gov/pubmed/17909079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-05-088435
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